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Bioaccumulation of Microplastics in Decedent Human Brains

Key Finding

Human brain tissue contained several times more microplastic than liver or kidney, and brains of people diagnosed with dementia showed markedly greater accumulation, concentrated in cerebrovascular walls and immune cells.

Summary

A Nature Medicine study analyzing postmortem human tissue found micro- and nanoplastics accumulating in the brain at far higher concentrations than in the liver or kidney, with levels appearing to rise over recent years. Brains of decedents with a documented dementia diagnosis carried the highest microplastic burden.

PUBLISHED IN

Nature Medicine

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Nature Medicine

Nature Medicine

February 1, 2025